[Frontiers in Bioscience 8, d440-450, January 1, 2003] 440 MOLECULAR EPIDEMIOLOGY OF TUBERCULOSIS
نویسنده
چکیده
1. Abstract 2. Introduction 3. Genotyping methods 3.1. Genetic markers 3.1.1. Insertion sequences 3.1.2. Short repetitive DNA sequences 3.2. Restriction fragment length polymorphism analysis 3.2.1. IS6110 RFLP analysis 3.2.2. PGRS RFLP analysis 3.3. PCR-based typing 3.3.1. Mixed-linker PCR 3.3.2. Spoligotyping 3.3.3. VNTR and MIRU-VNTR typing 3.4. Comparison of genotyping methods 4. Molecular epidemiological studies 4.1. Epidemiological applications of molecular techniques 4.2. Approach for systematic molecular epidemiological studies 4.3. Interpretation of molecular epidemiological studies 5. Perspectives 6. Acknowledgement 7. References
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